A gold color metal and enamel device 1 3/16 inches (3.02 cm) in width overall consisting of a maroon cross upon a disc quartered diagonally by four gold heads of wheat separating the four quarters of the disc (which are of white right and left, green at top and blue at bottom), the last quarter formed in the shape of an arrowhead overlapping the lower arm of the cross to its center; all above a green three-part scroll with the inscription SUPPORT IS OUR BUSINESS in gold letters.
The disc shape represents the state flower of Kansas, the sunflower, and is quartered by four heads of wheat to represent the industry for which the state is famous. The maroon medical cross stands for the mission of the unit and is shown behind the lower blue quarter which extends to the scroll in the shape of an arrowhead, representing the influence and contributions made by the Native Americans of the region in the development of the area. The upper quarter of green represents the state of Kansas, fertile and rich in wheat; the two side quarters symbolize by their shape and white color the optical nature of supplies handled by the unit. White is used also to represent the medical nature of the mission.
The distinctive unit insignia was originally approved for the 388th Medical Unit on 22 March 1983. It was redesignated for the 388th Medical Battalion with the description and symbolism revised effective 16 October 1994.